Application of special-purpose digital computers to rotorcraft real-time simulation

The use of an array processor as a computational element in rotorcraft real-time simulation is studied. A multilooping scheme was considered in which the rotor would loop over its calculations a number of time while the remainder of the model cycled once on a host computer. To prove that such a method would realistically simulate rotorcraft, a FORTRAN program was constructed to emulate a typical host-array processor computing configuration. The multilooping of an expanded rotor model, which included appropriate kinematic equations, resulted in an accurate and stable simulation

A real-time, dual processor simulation of the rotor system research aircraft

A real-time, man-in-the loop, simulation of the rotor system research aircraft (RSRA) was conducted. The unique feature of this simulation was that two digital computers were used in parallel to solve the equations of the RSRA mathematical model. The design, development, and implementation of the simulation are documented. Program validation was discussed, and examples of data recordings are given. This simulation provided an important research tool for the RSRA project in terms of safe and cost-effective design analysis. In addition, valuable knowledge concerning parallel processing and a powerful simulation hardware and software system was gained

Differences in Dopamine Function in Fibromyalgia

poster abstractObjective: Fibromyalgia (FM) is a debilitating pain disorder that affects 2% of the population. Many of the drugs prescribed to fibromyalgia sufferers are highly addictive, have limited clinical efficacy, and do not treat the cognitive symptoms of fibromyalgia. The neurobiological substrates of fibromyalgia are unknown, but there is evidence for involvement of altered dopaminergic transmission in pain disorders. Given that dopamine is essential for proper cognitive function, it is possible that fibromyalgia symptoms are partly mediated by abnormal dopaminergic functioning. However, the in vivo dopamine system in fibromyalgia patients has not been assessed. Thus, the objective of the current study was to ascertain how the dopamine system in fibromyalgia differs from healthy controls. Methods: [18F]-Fallypride (FAL) PET scanning was used to assess DA changes during a working memory task relative to a baseline task. Twelve patients with FM and twelve controls completed study procedures. Subjects received one FAL PET scan during a 2-back working-memory condition and one during a 0-back (attentional control) task. Results: Fibromyalgia subjects had higher baseline FAL binding potential (BPND) in the right amygdala and ventral pallidum relative to controls. FM subjects had lower baseline FAL BPND in frontal, temporal, and cingulate cortices. Voxel-wise paired t-tests were used to infer increases or decreases in FAL BPND (indicative of decreases or increases in dopamine, respectively) during 2-back performance. Fibromyalgia subjects had significant dopamine release in the ACC, left insula, OFC, and bilateral hippocampus during the 2-back task. Conversely, decreases in DA were detected in the posterior parietal cortex and vmPFC. In controls, dopamine appeared to decrease in the posterior parietal lobe, left hippocampus, and vmPFC during the 2-back task. No significant DA release was detected in controls. Self-reported pain ratings in fibromyalgia subjects were significantly associated with baseline FAL BPND in the ACC, bilateral ventral pallidum, amygdalae, and PAG. Conclusion: These data suggest that in fibromyalgia, abnormalities in dopamine function may be associated with both working memory and pain perception. Further studies are needed to further explore the potential associations between dopamine and cognitive performance and pain perception in FM

Dissipative Particle Dynamics with Energy Conservation

The stochastic differential equations for a model of dissipative particle dynamics with both total energy and total momentum conservation in the particle-particle interactions are presented. The corresponding Fokker-Planck equation for the evolution of the probability distribution for the system is deduced together with the corresponding fluctuation-dissipation theorems ensuring that the ab initio chosen equilibrium probability distribution for the relevant variables is a stationary solution. When energy conservation is included, the system can sustain temperature gradients and heat flow can be modeled.Comment: 7 pages, submitted to Europhys. Let

Superposition of macroscopic numbers of atoms and molecules

We theoretically examine photoassociation of a non-ideal Bose-Einstein condensate, focusing on evidence for a macroscopic superposition of atoms and molecules. This problem raises an interest because, rather than two states of a given object, an atom-molecule system is a seemingly impossible macroscopic superposition of different objects. Nevertheless, photoassociation enables coherent intraparticle conversion, and we thereby propose a viable scheme for creating a superposition of a macroscopic number of atoms with a macroscopic number of molecules.Comment: 4 pages, 2 figs, to appear in Phys. Rev. Let

Landau-Zener Problem for Trilinear Hamiltonians

We consider a nonlinear version of the Landau-Zener problem, focusing on photoassociation of a Bose-Einstein condensate as a specific example. Contrary to the exponential rate dependence obtained for the linear problem, a series expansion technique indicates that, when the resonance is crossed slowly, the probability for failure of adiabaticity is directly proportional to the rate at which the resonance is crossed.Comment: 4.5 pages, 1 figure, transferred to PRA; v2 adds discussion, clarification, and explicit numbers for Na and 87R

The roles of motivation and ability in controlling the consequences of stereotype suppression

Two experiments investigated the conditions under which previously suppressed stereotypes are applied in impression formation. In Experiment 1, the extent to which a previously suppressed racial stereotype influenced subsequent impressions depended on the race of the target who was subsequently encountered. Whereas impressions of race-unspecified targets were assimilated to the stereotype following its suppression, no such effects were observed when the target belonged to the racial group whose stereotype had been initially suppressed. These results demonstrate that when perceivers are motivated to avoid stereo-typing individuals, the influence of a stereotype that has been previously activated through suppression is minimized. Experiment 2 demonstrated that these processing goals effectively reduce the impact of suppression-activated stereotypes only when perceivers have sufficient capacity to enact the goals. These results suggest that both sufficient motivation and capacity are necessary to prevent heightened stereotyping following stereotype suppression

Identification of type III secretion inhibitors for plant disease management

Bacterial plant pathogens are among the most devastating threats to agriculture. To date, there are no effective means to control bacterial plant diseases due to the restrictions in the use of antibiotics in agriculture. A novel strategy under study is the use of chemical compounds that inhibit the expression of key bacterial virulence determinants. The type III secretion system is essential for virulence of many Gram-negative bacteria because it injects into the plant host cells bacterial proteins that interfere with their immune system. Here, we describe the methodology to identify bacterial type III secretion inhibitors, including a series of protocols that combine in planta and in vitro experiments. We use Ralstonia solanacearum as a model because of the number of genetic tools available in this organism and because it causes bacterial wilt, one of the most threatening plant diseases worldwide. The procedures presented can be used to evaluate the effect of different chemical compounds on bacterial growth and virulence

Vulnerability to bullying in children with a history of specific speech and language difficulties

This is an electronic version of an article published in Lindsay, Geoff and Dockrell, Julie and Mackie, Clare (2008) Vulnerability to bullying in children with a history of specific speech and language difficulties. European Journal of Special Needs Education, 23 (1). pp. 1-16. European Journal of Special Needs Education is available online at: http://www.informaworld.com/10.1080/0885625070179120